I have good experience with an Point Grey Grasshopper 2 for FISH (GS2-FW-14S5M-C) which I got used for a very reasonable price. It has some pattern
noise but it is OK for chromosomal FISH and IF. It captures chromosomal FISH signals nicely with an 40x.
I also have a PTGrey GS1 (GRAS-14S5M-C) but with this one I had some issues with MicroManager – in some cases MM got the frame from the previous
capture which led to the first image in a multi-channel z stack being from the wrong channel/filter. Also the GS1 had an Amp-glow issue on one short side.
If you need I can provide sample images, you can contact me off list.
Dr. med. Peter Braubach
Institut für Pathologie
Medizinische Hochschule Hannover
OE 5110, Carl-Neuberg-Str. 1, 30625 Hannover, Deutschland